Prenatal pollution exposure reduces heart stress response in infants

Exposure of mothers to particulate air pollution during pregnancy is linked to reduced heart response to stress in their six-month-old infants, according to a study which may lead to better prenatal care guidelines.
The study, published in the journal Environmental Health Perspectives, found that particulate air pollution exposure before birth may affect heart rate variability in six-month-old infants.
The researchers, including those from The Icahn School of Medicine at Mount Sinai in the US, studied 237 mothers and their infants, and used satellite data and air pollution monitors to determine the level of particulate air pollution the mothers were exposed to during pregnancy.
They said that heart rate variability to stressful experiences was essential for maintaining proper functioning of the cardiovascular, respiratory, and digestive systems, and was also central to emotional well-being, and resilience to stress.
Decreased heart rate variability, the study noted, is a risk factor for mental and physical health problems in later life.
Researchers said air pollution’s negative effect on heart rate variability was before found to cause heart disease, asthma, allergies, and mood or behavioral disorders in older children, adolescents, and adults.
In the current study, they found that with higher levels of the mother’s exposure to air pollution during pregnancy, there was less variability in the heart rate of infants in response to stress at six months of age.
“These findings, in combination with increasing worldwide exposure to particulate air pollution, highlight the importance of examining early-life exposure to air pollution in relation to negative medical, developmental, and psychological outcomes,” said study senior author Rosalind Wright from Mount Sinai Hospital.
The researchers said that identifying exposures to pollutants that disrupt key processes such as heart rate response may lead to prevention strategies early in life when they can have the greatest impact.
“Specifically, these findings support individual-level and policy-level action to reduce exposure to particulate air pollution exposure during pregnancy,” said the study’s first author Whitney Cowell of The Icahn School of Medicine at Mount Sinai. (PTI)