Researchers, including one of an Indian-origin, have found that the popular painkiller ibuprofen may have more significant effects on the liver than previously thought.
Ibuprofen belongs to a group of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs, widely used over the counter to treat pain and fever.
“It’s well-established that ibuprofen can cause heart problems and increase stroke risk, but the effects on the liver were less well understood, said study researcher Aldrin Gomes, Professor at University of California,. For the findings, Gomes, researcher Shuchita Tiwari and colleagues dosed mice with a moderate amount of ibuprofen for a week — equivalent to an adult human taking about 400 mg of the drug daily.
Then they used advanced mass spectrometry to capture information on all the metabolic pathways in liver cells. (IANS)
