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UK approves Pfizer’s vaccine, first shots roll out next week

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London, Dec 2: The UK on Wednesday became the first country to approve the Pfizer/BioNTech vaccine against COVID-19 after “rigorous” analysis by its independent regulator, paving the way for mass vaccinations from as early as next week among people at the highest risk of death from the deadly virus.
The British regulator, the Medicines and Healthcare products Regulatory Agency (MHRA), says the jab, which claims to offer up to 95 per cent protection against Covid-19 illness, is safe for roll out.
The UK government said the approval follows a “rigorous” analysis of the data, conducted at a faster pace but without any compromise on standards.
Prime Minister Boris Johnson welcomed the “fantastic” news and confirmed that the vaccine will begin to be made available from next week.
“It’s the protection of vaccines that will ultimately allow us to reclaim our lives and get the economy moving again,” Johnson, a COVID-19 survivor, said.
The vaccines require two doses 21 days apart, with strong immunity response kicking in after seven days of the second dose.
The MHRA said it will continue to monitor the data on a rolling basis once the vaccines are deployed among the British public.
“I am thrilled. Help is on its way… we can see the dawn. Let’s redouble our efforts to follow the lockdown rules,” said UK Health Secretary Matt Hancock.
“It’s been a very tough 2020 but 2021 will be brighter,” he said.
The UK government has formally accepted the recommendation from the MHRA, which means the two-dose vaccine can be injected into arms of high-risk categories within days.
Around 10 million doses should be available soon, with the first 800,000 arriving in the UK in the coming days.
“The vaccine will be made available across the UK from next week. The NHS [National Health Service] has decades of experience in delivering large scale vaccination programmes and will begin putting their extensive preparations into action to provide care and support to all those eligible for vaccination,” said a spokesperson for the Department of Health and Social Care (DHSC).
“This follows months of rigorous clinical trials and a thorough analysis of the data by experts at the MHRA who have concluded that the vaccine has met its strict standards of safety, quality and effectiveness,” the spokesperson said.
The UK’s Joint Committee on Vaccinations and Immunisations (JCVI) has published its advice for the priority groups to receive the vaccine, including care home residents, health and care staff, the elderly and the clinically extremely vulnerable.
Elderly people in care homes and care home staff are top of the priority list, followed by over-80s and health and care staff. Professor Wei Shen Lim of the JCVI told reporters at a Downing Street briefing that vaccine prioritisation has been based on the risk of death from Covid-19 and the hope is that “in phase one of the vaccination programme, 90 to 99 per cent of those who are most at risk of dying from Covid-19 will be covered”.
NHS Chief Executive, Simon Stevens, said the health service was preparing for “the largest-scale vaccination campaign in our country’s history”.
The joint vaccine, produced by American pharmaceutical giant Pfizer and German biotech firm BioNTech, had recently claimed trials suggested it works well in people of all ages, races and ethnicities. The UK is expected to receive a total of 40 million doses by the end of 2021, enough to vaccinate up to a third of the population, with the majority of doses anticipated in the first half of next year.
The Pfizer/BionTech formula is an mRNA vaccine that uses a tiny fragment of genetic code from the pandemic virus to teach the body how to fight Covid-19 and build immunity.
An mRNA vaccine has never been approved for use in humans before, with people only receiving them in clinical trials so far.
The UK government had stressed that the Covid-19 vaccine will only be authorised for supply by the UK’s independent regulator if it meets strict standards of quality, safety, and effectiveness, and if they are satisfied the vaccine can be consistently manufactured.
Experts reiterated that the MHRA approval means the vaccine is safe for human use.
The vaccine must be stored at around -70C and will be transported in special boxes, packed in dry ice. Once delivered, it can be kept for up to five days in a fridge. (PTI)

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